Antithrombotic agents and invasive procedures

for iPhone and iPad


Dosing in pediatric anesthesia, emergency medicine and intensive care

for iPhone and iPad


Here is an overview of the currently available apps


The app-solute helper to manage antithrombotic medication and invasvie procedures. Includes 'bridging' and 'cardiovascular risk'.


Dose according to age and weight in pediatric anesthesia, intensive care and emerency medicine.


Malignant hyperthermia (MH) ! This is the offical app of the European MH Group (EMHG) and the MH Association of the United States (MHAUS).

Congress app

Need an app for a smaller meeting ? This might be your solution. (currently iOS only and limited to a single lecture room).


These are the main features. See below for further details

NOTE CoaguSafe is not a substitute for medical advice. CoaguSafe is intended for educational purposes only.


Drugs interacting with the coagulation system can be listed by generic or brand name.

Drug groups

Drugs are grouped according to their mode of action. Learn about monitoring and antagonism.


Suspension of the drug before invasive procedures in a list and detail view.



Calculate thromboembolic risk, information about briding up to the procedure.

Cardiovascular risk

Estimate cardiovascular and surgical bleeding risk.


Several international, national and also local guidelines can be selected.


the app solution for management of invasive procedures in patients with antithrombotic agents

NOTE CoaguSafe is not a substitute for medical advice. CoaguSafe is intended for educational purposes only.

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When to pause an antithrombotic agent ?

CoaguSafe has a list of most antithrombotic agents. These can be sorted by generic or brand name. Recommendations for pausing (according to international guidelines) are already visible in list view. The detail view expands on high- or low-risk procedures and - if appropriate - on patients with renal insufficency.

Each drug belongs to a drug class, i.e. thrombin inhibitors, FXa inhibitors, glycoproteine IIbIIIa inhibitors and others. Mode of action and monitoring is described for each group.

For iPhone and iPad

On warfarin or new oral anticoagulant ?

Oral anticoagulation has to be suspended for many invasive procedures. These patients might need 'bridging' with low molecular weight heparin (LMWH), dependent on the thromboembolic risk.

The thromboembolic profile is dependent on:

  • Valvular risk factors
  • Atrial fibrillation and CHADS2 VA2Sc score
  • Probability of venous thromboembolism

Management of the new oral anticoagulants (NOAC) is frequently dependent on renal function. Therefore renal function is also accounted for.

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Cardiovascular and bleeding risk?

Pausing antithrombotic drugs is important before invasive procedures are performed. On the other hand there are situations in which such suspension of antithrombotic agents might not be recommended.

The cardiovascular risk (e.g. recent coronary stents - bare metal or drug-eluting) as well as bleeding risk of the invasive procedure can be estimated.

Based on these two estimations suggestions of the guidelines are presented.


CoaguSafe is based on international and national guidelines. After selection of a guideline the respective recommendations are presented. If a specific drug is not included in the selected guideline, then alternative recommendations are shown (and labelled with an asterix).

The following guidelines are currently included:

  • American society of regional anesthesia and pain therapy (ASRA)
  • Deutsche Gesellschaft für Anästhesie und Intensivmedizin (DGAI)
  • European society of anaesthesiology (ESA)
  • Kantonsspital St. Gallen
  • United Kingdom (AAGBI, OAA, RA-UK)
  • Österreichische Gesellschaft Anästhesiologie, Reanimation und Intensivmedizin (ÖGARI)

Should a particular guideline be missing, then drop me an email. On specific request local guidelines can also be included.

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optimized for iPhone and iPad

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Optimized for iPad and iPhone

NOTE AnaPaed is not a substitute for medical advice. AnaPaed is intended for educational purposes only.


Drugs are dosed according to weight and/or age and shown as mg/kg as well as ml.


All items can be ordanized in editable lists. 'Standard medication' is your favorties list.


Drug concentrations, brand names, position in list can be edited.


Add your own

New drugs can be added with custom concentration and weight or age dependent dosing.


Define a list of emergency drugs and Quickly select an age group to be suggested a weight.


A calculator to calculate dilutions and dosing of lyophilized drugs.


optimized for iPhone and iPad

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